Efficacy of Inactivated Fowl Cholera Vaccine in Chickens
Fowl cholera is highly prevalent bacterial disease in poultry population of India. Several areas of India have been reported with outbreaks of fowl cholera. Fowl cholera severely affects the health of flocks, causes morbidity and mortality. Drop in egg production with worsened egg quality also results due to poor health of flock. The disease is also prevalent in village chicken and vaccination is the effective tool to control the prevalence of the disease. In present research, 30 specific pathogen free birds were divided into vaccinated (Group 1; 20 birds) and control (Group 2; 10 birds) groups. Birds from group 1 were vaccinated with inactivated fowl cholera vaccine and 14 days later given booster dose. After 21 days of booster dose, both groups were challenged with virulent strain of fowl cholera disease. At 7 days interval blood was collected and serology was performed for presence of antibodies against the disease with ELISA technique. The vaccine was found effective with respect to serum titre and challenge study as well. From the research, it can be concluded that effective vaccination programs can control the prevalence fowl cholera disease.