PSM Biological Research <p style="text-align: justify;">PSM Biological Research (ISSN; 2517-9586) is a peer-reviewed, open access, multidisciplinary,&nbsp; international journal that publishes research on all aspects of biology and allied sciences.</p> en-US (PSM Biological Research) (MANI MUGHAL) Sat, 31 Jul 2021 00:00:00 +0000 OJS 60 Antioxidant and Anti-inflammatory Activities of Methanolic Extract of Marrubium deserti de Noé Leaves Nabil Ghedadba, Leila Hambaba, Messaoud Hachemi, Mohamed Sabri Bensaad Copyright (c) 2021 PSM Thu, 22 Jul 2021 00:00:00 +0000 Phytochemical and Bioactive Evaluation of Cissus rotundifolia and Maydis stigma Cultivated in Taiz, Yemen <p>The aim of the study was to investigate antioxidant and antibacterial activity of methanolic leaf extracts of <em>Cissus rotundifolia</em> (CR) and <em>Maydis stigma (corn silk) </em>type Zea mays L from Taiz -Yemen. Phytochemical analysis of <em>Cissus rotundifolia </em>extract indicated the presence of triterpenes, carbohydrates, and/or glycosides, tannins, flavonoids, coumarins, and saponins, and the <em>Maydis stigma (corn silk) </em>type Zea mays L extract indicated the presence of alkaloids triterpenes, carbohydrates, and/or glycosides, tannins, flavonoids, saponins, proteins and free amino acids. The extracts were tested against different bacteria such as <em>Pseudomonas aeruginosa</em>, Proteus and Klebsiella. The methanol extracts of <em>Cissus rotundifolia </em>showed effective free radical scavenging in the DPPH assay.</p> Ahmed Y. Mubarak, Maher A. Almaqtari, Hussein Gumaih, Afrah Alasbahy Copyright (c) 2021 PSM Thu, 22 Jul 2021 00:00:00 +0000 Epidermal Properties of Aloe vacillans Forsskål Leaf and Its Taxonomical Significance in Classifying its Two Forms <p>About 14 leaf epidermal characters (6 epidermal cell properties &amp; 8 stomatal properties) of two forms (red-flowered &amp; yellow-flowered forms) of <em>Aloe vacillans </em>Forsskål (Endemic Species to South West of Arabian Peninsula) were investigated. Only two epidermal cell properties and three stomatal properties show high significance in distinguishing between the two forms of<em> A. vacillans</em>. Moreover; 12 epidermal quantitative characters were subjected to numerical analysis (UPGMA), and the resulted dendrogram segregated the two examined forms at a relatively high similarity level (93.53%). This confirms that the two forms (red form and yellow form) of <em>A. vacillans</em> are two different infra-specific taxa under <em>A. vacillans</em>, which were described as <em>A. audhalica </em>Lavranos and Hardy and <em>A. dhalensis </em>Lavranos.</p> Hassan M. Ibrahim, Atheer Radman Alshaibani, Abdul Nasser A. Al-Gifri Copyright (c) 2021 PSM Thu, 22 Jul 2021 00:00:00 +0000 A Comparative Study to Assess the Quality of Different Marketed Brands of Metformin HCl <p>The present work reported quality assessments and stability studies of metformin hydrochloride in various brands with a label claim of 500 mg marketed in the capital Sana'a, Yemen. Physical parameters including thickness, diameter, hardness, friability, weight variation, and disintegration time were evaluated.&nbsp; Assay tests and dissolution rates were carried out using HPLC-UV and spectrophotometric methods respectively. All investigations were done at purchase time and after one month, three months, and six months storage conditions under an accelerated stability environment (40±2°C and 75±5% RH). The results showed that all brands of metformin hydrochloride complied with the official specification for thickness, diameter, hardness, friability, weight variation, disintegration time, dissolution, and assay tests.&nbsp; Assay evaluation results revealed that all tested brands have met the acceptance criteria (95%-105%) with exception of ME1 samples stored for three months whose values (94.29%) were lower than the acceptable limit and ME4 (105.95%) and ME5 (105.66%) stored for one month that was higher than the acceptable range.</p> Anass A. Alnedhary, Abdualqawi A. Numan, Mahfoudh M. AL-Hammadi, Fatima A. Murshed, Huda M. Dubais Copyright (c) 2021 PSM Thu, 22 Jul 2021 00:00:00 +0000