PSM Biological Research 2022-10-31T00:00:00+00:00 PSM Biological Research Open Journal Systems <p style="text-align: justify;">PSM Biological Research (ISSN; 2517-9586) is a peer-reviewed, open access, multidisciplinary,&nbsp; international journal that publishes research on all aspects of biology and allied sciences.</p> Prevention and Management of Pre-Eclampsia and Eclampsia in Tertiary Care Hospital of Islamabad 2022-08-27T08:53:59+00:00 Mehak Nimra Hamza Irshad Muhammad Murtaza Hasnain Sheikh Ishaque Aamir Muhammad Akram <p>Pre-eclampsia is a syndrome that is usually defined as the onset of hypertension and proteinuria after 20 weeks of gestation in previously normotensive, non-proteinuric pregnant women. If untreated, pre-eclampsia progresses to a major neurological complication known as eclampsia. The aim of this study was to analyze the management of pre-eclampsia and eclampsia and to explore the role of clinical pharmacists in the prevention of pre-eclampsia and eclampsia. A prospective study of 20 patients on the management of eclampsia and pre-eclampsia was carried out at the Mother and Child Health Hospital PIMS, Islamabad. Data analysis showed that 75% of women have pre-eclampsia and 25% of women have eclampsia. The primary treatments given to the patients consisted of intravenous infusions of magnesium sulfate, methyldopa, and nifedipine. Of these, 60% received magnesium sulfate and 90% received oral methyldopa and nifedipine. The increased workload of nurses and physicians due to the increase in the number of patients with pre-eclampsia and eclampsia requires clinical pharmacists to work side-by-side with nursing staff and physicians, resulting in reduced morbidity and mortality, and improved quality of life for mothers and infants.</p> 2022-10-20T00:00:00+00:00 Copyright (c) 2022 PSM Evaluation of Antibiotic-resistant Bacteria and Physicochemical Parameters in Groundwater, Impacted by Dairy Farms in Hatillo, Puerto Rico 2022-08-05T17:19:07+00:00 Francisco Bello Lourdes Echevarría <p>The dairy industry produces many contaminants. This industry constantly uses a water resource in its processes, which carries these contaminants through the soil to groundwater supplies. Dairy cows excrete a significant fraction of antibiotics, posing a substantial risk that active or unchanged metabolites into the environment and leach to groundwater. The aim of this study is to determine if the dairy industry represents a source of bacterial contamination to groundwater, analyze the resistance to antibiotics in the identified bacteria and evaluate the risk to which nearby communities are exposed when they use them as drinking water. Samples were taken from three wells revealing antibiotic-resistant autochthonous bacteria. The physicochemical parameters were analyzed. Eight different types of bacteria were identified, <em>Bacillus sp</em>., <em>Micrococcus sp.</em>, <em>Acinetobacter baumannii</em>, <em>Enterobacter aerogenes</em>, <em>Enterobacter cloacae</em>, <em>E. coli</em>, <em>Pseudomonas aeruginosa</em>, and <em>Pseudomonas putida</em>. Ammonium and nitrate in wells A and B exceeded limits, turbidity in wells A and C exceeded limits. However, the pH and temperature were within limits. Dairy farms can be a source of contamination to groundwater. Improvements in manure management are recommended using more profitable technologies in the transformation of waste from dairy industries. These contaminants can migrate through the soil and reach groundwater supplies, which can contribute to potential impact on public health and the environment.</p> 2022-10-20T00:00:00+00:00 Copyright (c) 2022 PSM