Plants as Antidiabetic Agents: Traditional Knowledge to Pharmacological Validation

  • Manzoor Ullah Department of Botany, University of Science and Technology, Bannu (28100) Khyber Pakhtunkhwa, Pakistan.
  • Madiha Zaynab College of Life Science, Fujian Agriculture and Forestry University, Fuzhou 350002, PR. China.
  • Mahpara Fatima College of Crop Science, Fujian Agriculture and Forestry University, Fuzhou 350002, PR. China.
  • Safdar Abbas Department of Biochemistry, Quid-e-Azam University, Islamabad, Pakistan.
  • Yasir Sharif College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, PR China.
  • Taimoor Hassan Farooq College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, PR China.
  • Muhammad Hammad Zaffar Department of Life Science, University of Agriculture Faisalabad, Pakistan.
  • Razi Ullah Institute of Chemical Sciences, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan.
  • Saad Ullah Khan Department of Botany, University of Science and Technology, Bannu (28100) Khyber Pakhtunkhwa, Pakistan.
  • Wahid Hussain Department of Botany, University of Peshawar, Khyber Pakhtunkhwa, Pakistan.
  • Ihsan Ullah Department of Botany, University of Science and Technology, Bannu (28100) Khyber Pakhtunkhwa, Pakistan.
  • Shabnam Shaheen Higher Education Department, Khyber Pakhtunkhwa, Pakistan.
  • Maroof Ali Department of Biological Sciences and Chemistry, College of Arts & Sciences, University of Nizwa, Sultanate of Oman.
Keywords: Antidiabetic medicinal plants; traditional knowledge; pharmacological validation.

Abstract

Diabetes is the most devastating and serious of all metabolic diseases. The available natural remedies are considered as a valuable source of therapeutic agents. A scientific validation of the reported antidiabetic plants on the basis of their traditional use may pave the way for the development of novel and effective antidiabetic drugs. Such approaches are the necessity of the day because the available medicines are insufficient to manage all the consequences of diabetes, and the economic problems and a shortage of current therapies in most developing countries. This review comprises information about antidiabetic medicinal plants of Pakistan with respect to traditional knowledge. The article also includes the in-vitro or in-vivo potential, toxicity, mode of action, and perspective for future research. This effort may serve as a leading point for the formulation of novel herbal mixtures, development of antidiabetic drugs or their precursors.

Published
2018-08-18
How to Cite
Ullah, M., Zaynab, M., Fatima, M., Abbas, S., Sharif, Y., Farooq, T., Zaffar, M., Ullah, R., Khan, S., Hussain, W., Ullah, I., Shaheen, S., & Ali, M. (2018). Plants as Antidiabetic Agents: Traditional Knowledge to Pharmacological Validation. PSM Biological Research, 3(3), 111-119. Retrieved from http://journals.psmpublishers.org/index.php/biolres/article/view/210
Section
Review Articles